The fire endangers the unique biodiversity of Santa Rosa Island, including six plant species that exist nowhere else in the world. Wildlife such as island foxes, spotted skunks, and elephant seals are also at risk. Additionally, smoke from the fire has affected air quality in the Los Angeles region, with potential health implications for residents. The fire's rapid spread and lack of containment highlight the ongoing risk to both the environment and human safety. The island remains closed to visitors for the foreseeable future.